Affiliations:
Site/Title
- Moffitt Cancer Center and Research Institue/ Director of NeuroPathology and Cell Biology
and Autopsy Service
H. Lee Moffitt Cancer Center
12902 Magnolia Drive
Tampa, FL- 33612
- James A Hailey VA Hospital/ Director of NeuroPathology and Cell Biology
Qualifications:
- Diplomate of the American Board of Pathology and Cell Biology
- Anatomic Pathology and Cell Biology 6/92, Subspecialty: NeuroPathology and Cell Biology 6/92
- 1989-1991 Fellowship - Adult and Pediatric NeuroPathology and Cell Biology Vancouver
General Hospital and B.C.'s Children's Hospital, University of British
Columbia, Vancouver, Canada
- 1987-1989 Residency - Anatomic Pathology and Cell Biology UMDNJ - Affiliated
Hospitals / New Jersey Medical School, Newark, NJ
- 1982-1987 Ph.D.(Experimental NeuroPathology and Cell Biology) Graduate School
of Biomedical Sciences, UMDNJ, Newark, NJ
- 1974-1982 M.D. Sind Medical College, University of Karachi,
Pakistan.
Expertise:
- Diagnostic expertise in all aspects of Pediatric and Adult NeuroPathology and Cell Biology,
with particular interests in neuro-oncology and muscle and nerve biopsies.
Research Interests:
- Research interest in neuro-oncology has been directed to the "phakomatoses".
Markers of malignant progression such as CD 44 and p53 expression as
well as studies on expression of neurofibromin and erythropoietin are
ongoing. Vascular Pathology and Cell Biology both in neuro-oncology and dementia are
areas of significant interest and will continue to be explored both
with the use of human tissue and animal models. Clinical research interests
include atypical CNS infections particularly PRION diseases.
Memberships:
- 10/01-Present Co-Chair, Neuroscience Seminar Series
- 9/01-Present USF-COM By-Laws Committee
- 6/00-Present, Secretary, USF-Pathology and Cell Biology Alumni Foundation
- 6/00-Present, Departmental Delegate - USF College of Medicine Faculty
Council
- 8/98-Present, Pathology and Cell Biology Residency Program Committee
- 6/98-Present, Ph.D. - Neurosciences Concentration Committee, USF
- 5/98-Present, Founding Faculty, USF-Neuroscience Program
- 9/98-Present, Member in Residence, H. Lee Moffitt Cancer Ctr and Research
Institute
- 6/98-Present, Member, NABTT (New Approaches to Brain Tumor Therapy)
NCI Consortium
- 5/96-present, Assistant editor - Journal of Neuroimaging
- 8/99-Present, Member - Editorial Board, J. NeuroPathology and Cell Biology and Experimental
Neurology
Previous Positions:
- 1/94 - 3/98 Assistant Professor, University of Florida
- 1/92 - 12/93 Clinical Fellow/Instructor, Department of Pathology and Cell Biology,
UF
Publications:
- Emery JA, Roper SN, Rojiani AM: White Matter Neuronal
Heterotopia in Temporal Lobe Epilepsy: A Morphometric and Immunohistochemical
Study. J Neuropathol Exp Neurol 1997; 56:1276-82
- Gold M, Rojiani AM, Murtaugh R: 66 yr old Woman With a
Rapidly Progressive Dementia and Basal Ganglia Involvement - (Sporadic
Creutzfeldt-Jakob Disease), A Neuroimaging Clinico-pathologic Correlation.
J. Neuroimaging 1997; 7:171-175
- Hampton TA, Scheithauer BW, Rojiani AM, Kovacs K, Horvath
E, Vogt P: Salivary Gland-Like Neoplasms of the Sellar Region.
Am J Surg Pathol 1997; 21(4): 424-434
- Salzman K, Rojiani AM, Buatti J, Quisling RG, Marcus RB,
Maria BL, Mickle JP, Kedar A: Primary Intracranial Germ Cell Tumors:
Clinicopathologic Review of 32 cases. Ped Pathol Lab Med 1997;
17(5) 713-727
- Clark D, Kersting R, Rojiani AM: Erythropoietin Immunolocalization
in Renal Cell Carcinoma Modern Pathology and Cell Biology 1998; 11(1)24-28
- Rojiani AM, Cho ES: Neuropathologic Applications of Immunohistochemical
Fiber Typing in the Non-Neoplastic Muscle Biopsy. Modern Pathology and Cell Biology
1998; 11(4)334-338
- Cibula JE, Strickler ST, Quisling RG, Uthman BM, Friedman W, Rojiani
AM: Calcified Cystic Lesions in a Patient with Epilepsy and
Progressive Dementia. (Multiple Cavernous Hemangiomas) A Neuroimaging
Clinico-pathologic Correlation. J Neuroimaging 1998; 8:97-102
- Rojiani AM: Book Review- "Cell Biology and Pathology and Cell Biology
of Myelin: Evolving Biological Concepts and Therapeutic Approaches"
Altschul Symposia Series. 1998 J Neuropathol Exp Neurol 57 (5)
- Li Lingyun, Rojiani AM, Siemann DW: Targeting the Tumor
Vasculature with Combrettastatin A-4Disodium Phosphate: Effects on
Radiation Therapy. Int J Rad Oncol Biol Physics 1998; 42:899-903
- Juul SE, Yachnis AT, Rojiani AM, Christensen RD. Immunohistochemical
Localization of Erythropoietin and its Receptor in the Developing
Human Brain.Ped Devel Pathol 1999:148-158
- Parchi P, Giese A, Capellari S, Brown P, Schulz-Schaeffer J, Windl
O, Zerr I,Budka H, Kopp N, Piccardo P, Poser S, Rojiani AM,
Streichenberger N, Julien J, Vital C, Ghetti B, Gambetti P, Kertzscmar
HA: Classification of Sporadic Creutzfeldt-Jakob Disease based
on Molecular and Phenotypic Analysis of 300 Subjects. Ann Neurol
1999; 46:224-233
- Cho ES, Rojiani AM: "NeuroPathology and Cell Biology of HIV Encephalitis."
2000-ASCP Check Sample Series
- Rasmussen SA, Overman J, Thomson SAM, Colman SD, Abernathy CR, Trimpert
RE, Moose R, Virdi G, Roux K, Bauer M, Rojiani AM, Maria BL,
Muir D, Wallace MR. Chromosome 17 loss-of-heterozygosity in benign
and malignant tumors in neurofibromatosis type 1. Genes Chromosomes
Cancer 2000, 28:425-431
- Marmol-Strickland L, Fessler R, Rojiani AM. Necrotizing
Sarcoid Granulomatosis Mimicking an Intracranial Neoplasm: Clinicopathologic
Features and Review of the Literature. Mod Pathol 2000; 13(8)
909-913
- Wiranowska M, Rojiani AM, Gottschall P, Moscinski L, Johnson
J, Saporta S: CD44 Expression and MMP2 Secretion by Mouse Glioma
Cells: Effect of Interferon and anti-CD44 antibody. Anticancer
Research 2000; 20:4301-4306
- Eisenschenk S, Triggs WJ, Pearl GS, Rojiani AM: Proximal
Myotonic Myopathy (PROMM): Clinical, Histologic and Molecular Genetic
Features. Ann Clin Lab Sci 2001; 31(2):140-146
- Mori T, Paris D, Town T, Rojiani AM, Sparks LD, Delledonne
A, Crawford F, Abdullah LI, Humphery JA, Dickson DW, Mullan MJ:
Choleserol Accumulates in Senile Plaques of Alzheimer Disease Patients
and in Transgenic APPsw Mice J Neuropathol Exp Neurol 2001; 60:778-785
- Tan J, Town T, Mori T, Obregon D, Wu Y, DelleDonne A, Rojiani
AM, Crawford F, Flavell RA, Mullan M: CD40 is Expressed and
Functional On Neuronal Cells. EMBO 2002; 21 (4) 643-652
- Li Lingyun, Rojiani AM, Siemann DW: Preclinical Evaluations
of Therapies Combining the Vascular Targeting Agent Combretastatin
A-4 Disodium Phosphate and Conventional Anticancer Therapies in the
Treatment of Kaposi's Sarcoma Acta Oncologica, 41(1) 91-97, 2002
- Rojiani AM, Li Lingyun, Rise L, Siemann DW: Activity of
the Vascular Targeting Agent Combretastatin A-4 Disodium Phosphate
in a Xenograft Model of AIDS-Associated Kaposi's Sarcoma. Acta
Oncologica, 41(1) 98-105, 2002
- Bloomston, M, Shafii A, Zervos EE, Rojiani AM, Rosemurgy
AS: MMP-2 and TIMP-1 are Derived From, Not in Response to, Pancreatic
Cancer. J Surgical Res 102 (1): 35-38, 2002
- Jantzen PT, Connor KE, DiCarlo G, Wenk GL, Wallace JL, Rojiani
AM, Coppola D, Morgan D, Gordon MN: Microglial Activation and
Aß Deposit Reduction Caused by a Nitric Oxide releasing NSAID,
NCX-2216, in APP+PS1 Transgenic Mice J Neurosci 22(6) 2246-2254,
2002
- Siemann DW, Mercer E, Lepler S, Rojiani AM: Vascular Targeting
Agents Enhance Chemotherapeutic Agent Activities In Solid Tumor Therapy
Int J Ca 99;1-6, 2002
- Siemann DW, Rojiani AM: Enhancement of Radiation Therapy
by the Novel Vascular Targeting Agent ZD6126. Int J Rad Oncol
Biol Physics 53(1) 164-171, 2002
- Jennings JW, Rojiani AM, Brem SS, Murtagh R: Necrotizing
Neurosarcoidosis Masquerading As a Left Optic Meningioma: Case Report.
Am J Neuroradiology 2002; 23:660-662
- Rojiani AM and Vale F: Book Chapter: "" Skeletal
Muscle Biopsy Techniques: Practice and Procedures" in "Skeletal
Muscle: Pathology and Cell Biology, Diagnosis and Management of Disease" Eds:
Preedy VR and Peters TJ.; Greenwich Medical Media Ltd., London. 2002
( In press)
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